Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
KIRC | rs403981 | chr21:46020066 | A/G | 5.37E-5 | 521 | 16.37 | 36.4 | 40.58 | KM Plot |
KIRC | rs404341 | chr21:46020242 | A/G | 3.06E-5 | 517 | 16.37 | 34.87 | 42.27 | KM Plot |
KIRC | rs4112785 | chr1:152533115 | G/C | 6.48E-5 | 524 | 35.6 | 44.3 | 37.77 | KM Plot |
KIRC | rs41284519 | chr6:31388522 | C/T | 9.52E-6 | 517 | 38.95 | 45.93 | 1.88 | KM Plot |
KIRC | rs4130522 | chr3:48352313 | G/A | 3.27E-5 | 523 | 39.62 | 41.27 | 19.13 | KM Plot |
KIRC | rs4141097 | chr7:46580508 | T/C | 5.18E-5 | 518 | 47.58 | 33.8 | 28.7 | KM Plot |
KIRC | rs4240885 | chr1:152529850 | G/C | 5.85E-5 | 525 | 35.6 | 44.05 | 37.77 | KM Plot |
KIRC | rs4274583 | chr2:67538600 | A/G | 1.9E-7 | 525 | 40.57 | 37.7 | 2.03 | KM Plot |
KIRC | rs4318565 | chr3:96081510 | C/T | 2.37E-10 | 527 | 3.37 | 41.27 | 38.93 | KM Plot |
KIRC | rs4330675 | chr8:125488907 | C/T | 2.25E-5 | 527 | 38.9 | 45.68 | 4.7 | KM Plot |
KIRC | rs4336952 | chr10:117674244 | G/T | 3.4E-5 | 527 | 42.33 | 22.47 | 22.17 | KM Plot |
KIRC | rs4364452 | chr6:165359668 | T/C | 2.07E-5 | 527 | 17.28 | 41.53 | 39.7 | KM Plot |
KIRC | rs4371540 | chr3:48353543 | G/A | 3.09E-5 | 523 | 39.53 | 41.27 | 19.13 | KM Plot |
KIRC | rs4374405 | chr2:2620063 | C/T | 4.06E-5 | 521 | 38.98 | 44.57 | 8.35 | KM Plot |
KIRC | rs4392440 | chr3:48343920 | C/T | 3.14E-5 | 521 | 39.62 | 40.93 | 19.13 | KM Plot |